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Frances H Arnold

The Nobel Prize in Chemistry 2018

Born: 25 July 1956, Pittsburgh, PA, USA

Affiliation at the time of the award: California Institute of Technology (Caltech), Pasadena, CA, USA

Prize motivation: “for the directed evolution of enzymes”

 

Work

Evolution – the adaption of species to different environments – has created an enormous diversity of life. Frances Arnold has used the same principles – genetic change and selection – to develop proteins that solve humankind’s chemical problems. In 1993, Arnold conducted the first directed evolution of enzymes, which are proteins that catalyze chemical reactions. The uses of her results include more environmentally friendly manufacturing of chemical substances, such as pharmaceuticals, and the production of renewable fuels.

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